| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802560 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 9 Pages |
Abstract
⺠Structural and functional properties of AAA-ATPases in ribosome biogenesis are summarized. ⺠The AAA-ATPases Rea1, Rix7 and Drg1 are essential for ribosome biogenesis in yeast. ⺠Rix7 and Drg1 are related to Cdc48, while Rea1 shares similarity to motor protein dynein. ⺠Rea1, Rix7 and Drg1 promote the release of biogenesis factors from nucleolar, nucleoplasmic and cytoplasmic pre-60S intermediates. ⺠The release of maturation factors by AAA-ATPases is critical for downstream maturation of pre-60S particles.
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Authors
Dieter Kressler, Ed Hurt, Helmut Bergler, Jochen BaÃler,