Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802561 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 7 Pages |
Abstract
⺠The R2TP (Rvb1-Rvb2-Tah1-Pih1) complex was identified in 2005 as an Hsp90 associated complex. ⺠The R2TP complex is conserved from yeast to higher eukaryotes. ⺠The complex is involved in box C/D snoRNP biogenesis. ⺠The complex is required for phosphatidylinositol-3 kinase-related protein kinase (PIKK) signalling. ⺠R2TP is involved in RNA polymerase II assembly.
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Authors
Yoshito Kakihara, Walid A. Houry,