Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802574 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 10 Pages |
Abstract
⺠Vps4 is a type-I AAA ATPases that functions with ESCRT-III in the deformation and fission of membranes. ⺠Vps4-mediated membrane fission plays an important role for MVB vesicle formation, cytokinesis and viral budding. ⺠Vps4 posses a dynamic quaternary structure that is regulated by the bound nucleotide and co-factors.
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Authors
Christopher P. Hill, Markus Babst,