| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802586 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 10 Pages |
Abstract
⺠Sphingosine-1-phosphate induces α1B-adrenergic receptor phosphorylation. ⺠IGF-I and EGF also induce this effect and increase sphingosine kinase activity. ⺠A sphingosine kinase-1 dominant-negative mutant reduced growth factor action. ⺠Similar effects are produced by S1P1 receptor knockdown. ⺠Sphingosine-1-phosphate is an autocrine mediator in the growth factor's effects.
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Authors
Jean A. Castillo-Badillo, Tzindilú Molina-Muñoz, M. Teresa Romero-Ávila, Aleida Vázquez-MacÃas, Richard Rivera, Jerold Chun, J. Adolfo GarcÃa-Sáinz,