| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802591 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 8 Pages |
Abstract
⺠The EGFR kinase inhibitor AG556 suppresses hEAG1 current. ⺠Tyrosine phosphorylation of the channel protein is also inhibited by AG556. ⺠These inhibitory effects are countered by the PTP inhibitor orthovanadate. ⺠Tyr90, Try344 and Try485 are responsible for the tyrosine phosphorylation.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Wei Wu, Ming-Qing Dong, Xing-Gang Wu, Hai-Ying Sun, Hung-Fat Tse, Chu-Pak Lau, Gui-Rong Li,