Article ID Journal Published Year Pages File Type
10802592 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2012 8 Pages PDF
Abstract
► PP2A phosphatase regulates 105 kDa NEDD9 phosphoform. ► PP2A interacts with the Serine-Rich region (SRR) of NEDD9. ► Constitutive phosphorylation of NEDD9 S369 in the SRR promotes cell spreading. ► The tumour suppressor PP2A suppresses NEDD9-mediated spreading and switch to mesenchymal morphologies.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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