Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802592 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 8 Pages |
Abstract
⺠PP2A phosphatase regulates 105 kDa NEDD9 phosphoform. ⺠PP2A interacts with the Serine-Rich region (SRR) of NEDD9. ⺠Constitutive phosphorylation of NEDD9 S369 in the SRR promotes cell spreading. ⺠The tumour suppressor PP2A suppresses NEDD9-mediated spreading and switch to mesenchymal morphologies.
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Authors
Peta Bradbury, Maha Mahmassani, Jessie Zhong, Kylie Turner, Andre Paul, Nicole M. Verrills, Geraldine M. O'Neill,