| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802600 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 13 Pages |
Abstract
⺠Ectopic expression of p20 leads to paraptosis-like cell death in E1A/DNp53 BMK cells. ⺠This p20-induced pathway is characterized by a rise in ER Ca2+ and ER vacuolization. ⺠Cell death and ER vacuolization can be delayed by Bcl2b5 in the absence of Bax/Bak. ⺠ER localized Bcl2 can exert a pro-survival effect in the absence of Bax/Bak.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Hannah M. Heath-Engel, Bing Wang, Gordon C. Shore,