| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802627 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 10 Pages |
Abstract
⺠Gefitinib resistance showed sustained TM4SF5 expression and EMT upon gefitinib treatment. ⺠T790M EGFR introduction into gefitinib-sensitive cells showed EMT and increased TM4SF5 level. ⺠Regulation of TM4SF5 expression resulted in modulation of gefitinib resistance. ⺠Suppression of TM4SF5-mediated effects also resulted in reduced gefitinib resistance.
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Authors
Mi-Sook Lee, Hwang-Phill Kim, Tae-You Kim, Jung Weon Lee,