| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802641 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 8 Pages |
Abstract
⺠Autophagy and endosomal degradation processes do converge and also contain common molecules ⺠Rab7 protein acts in a critical point of maturation process of both autophagosomes and endosomes ⺠Rab7 takes part in the transportation of autophagosomes and endosomes towards lysosomal degradation ⺠The action of Rab7 in autophagy and endocytosis is highly regulated ⺠The control of Rab7 may provide a means to control diseases in which autophagy or endocytosis is disturbed.
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Authors
Juha M.T. Hyttinen, Minna Niittykoski, Antero Salminen, Kai Kaarniranta,