| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802648 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 11 Pages |
Abstract
⺠An HPS1 isoform encoded by a transcript lacking exon 9 interacts with HPS4 ⺠The central region of HPS4 protein interacts dually, with either the N- or C-terminus of HPS1 ⺠Interacting regions of HPS1 and HPS4 exist as soluble and membrane-associated forms ⺠Missense mutations within interacting regions of HPS1 alter its stability ⺠Membrane association of HPS1 and HPS4 depends upon specific regions of these proteins
Keywords
FBSDUFIgGNaClBLOCeGFPHPSDMEMRT-PCRDulbecco's modified Eagle's mediumoculocutaneous albinismLysosome-related organelleimmunoglobulin GBleedingdomain of unknown functionSodium chloridefetal bovine serumHermansky–Pudlak syndromeLAMP-2hemagglutininpatlysosome-associated membrane protein 2enhanced green fluorescent protein
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Authors
Carmelo Carmona-Rivera, Dimitre R. Simeonov, Nicholas D. Cardillo, William A. Gahl, Carmen L. Cadilla,