| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802650 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 8 Pages |
Abstract
⺠Oxidized low density lipoprotein (ox-LDL) was proven to inhibit aldehyde dehydrogenase2 (ALDH2) activity in a time- and concentration-dependent manner. ⺠We report that poly(ADP-ribose) polymerase (PARP) is involved in the inhibition of ALDH2 activity by reactive oxygen species. ⺠We found the role of PARP on ALDH2 dehydrogenase activity might be mediated by SIRT3 expression.
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Authors
Shu-jian Wei, Jun-hui Xing, Bai-lu Wang, Li Xue, Jia-li Wang, Rui Li, Wei-dong Qin, Juan Wang, Xu-ping Wang, Ming-xiang Zhang, Yu-guo Chen,