Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802675 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 9 Pages |
Abstract
⺠We found that HDACIs induced EMT in cancer cells to facilitate cancer progression. ⺠In CNE2, LoVo, HepG2, HDACIs up-regulate Snail and Vimentin and down-regulate E-cadherin. ⺠We provided that Snail plays an important role in the HDACI-induced EMT. ⺠It shows that more attention should be paid to the cancer treatment using HDACIs.
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Authors
Guan-Min Jiang, Hong-Sheng Wang, Fan Zhang, Kun-Shui Zhang, Zong-Cai Liu, Rui Fang, Hao Wang, Shao-Hui Cai, Jun Du,