Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802678 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 6 Pages |
Abstract
⺠Plasma CD16 in humans is generated by ADAM protease activity. ⺠ADAM17 cleaves CD16a and CD16b in activated NK cells and neutrophils, respectively. ⺠CD16b undergoes ectodomain shedding in apoptotic neutrophils by ADAM17. ⺠Unlike human CD16, mouse CD16 is not efficiently regulated by ectodomain shedding.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Yue Wang, Jianming Wu, Robert Newton, Nooshin S. Bahaie, Chunmei Long, Bruce Walcheck,