Article ID Journal Published Year Pages File Type
10802678 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2013 6 Pages PDF
Abstract
► Plasma CD16 in humans is generated by ADAM protease activity. ► ADAM17 cleaves CD16a and CD16b in activated NK cells and neutrophils, respectively. ► CD16b undergoes ectodomain shedding in apoptotic neutrophils by ADAM17. ► Unlike human CD16, mouse CD16 is not efficiently regulated by ectodomain shedding.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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