Article ID Journal Published Year Pages File Type
10802686 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2013 9 Pages PDF
Abstract
► The weak PARP inhibitor 3-aminobenzamide (3AB) protected cells from phototoxicity. ► 3AB prevented both apoptosis and necrosis. ► Specific PARP inhibitors or PARP-1 silencing sensitized cells to phototoxicity. ► The protective effect of 3AB is not due to PARP inhibition.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism
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