| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802709 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 11 Pages |
Abstract
⺠Most of the organellar proteins are synthesized with N-terminal targeting peptides. ⺠Targeting peptides are cleaved off inside the organelles by processing peptidases. ⺠Precursors can be trimmed to increase stability or for intraorganellar routing. ⺠The cleaved targeting peptides are degraded by the organellar peptidasome, PreP. ⺠Dysfunctions of processing proteases are associated with human diseases.
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Authors
Pedro Filipe Teixeira, Elzbieta Glaser,