Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802715 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 10 Pages |
Abstract
⺠The retrograde response compensates for mitochondrial dysfunction accumulating over a cell's lifetime. ⺠Autophagy and mitophagy provide mitochondrial quality control. ⺠Age-asymmetry in segregation of dysfunctional mitochondria is another quality control mechanism. ⺠Mitochondrial quality control constitutes a complex network of processes that requires a systems approach to understand fully.
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Authors
S. Michal Jazwinski,