Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802742 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 8 Pages |
Abstract
⺠Glucocorticoid receptor binds to the D-loop of the mitochondrial DNA of HepG2 cells. ⺠DEX induces OXPHOS gene expression by the mitochondrial glucocorticoid receptor. ⺠DEX induces mitochondrial transcription factors gene expression. ⺠DEX-induced mitochondrial transcription maintained in the presence of α-amanitin. ⺠Mitochondrial GR activates OXPHOS enzyme synthesis and mitochondrial ATP production.
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Authors
Anna-Maria G. Psarra, Constantine E. Sekeris,