| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802743 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 5 Pages |
Abstract
⺠The anti-apoptotic effect of lactoferrin on neutrophils is dependent on its iron saturation status. ⺠The anti-apoptotic effect of lactoferrin is mediated at an early stage in neutrophil apoptosis. ⺠Lactoferrin inhibits generation of ceramide and activation of caspase 8 and Bax, as well as Bid cleavage and loss of Mcl-1.
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Authors
Nigel Francis, See Heng Wong, Peter Hampson, Keqing Wang, Stephen P. Young, Hans Peter Deigner, Michael Salmon, Dagmar Scheel-Toellner, Janet M. Lord,