Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802761 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 13 Pages |
Abstract
⺠The diversity in the structures of BH3-only proteins reflects a range of functions. ⺠The mechanism(s) and importance of BH3-only proteins binding to membranes. ⺠BH3-only proteins activate and inhibit multi-region Bcl-2 family proteins. ⺠BH3-only proteins at the endoplasmic reticulum function in apoptosis and autophagy. ⺠BH3-mimetics are potential drugs for cancer therapy.
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Authors
Aisha Shamas-Din, Hetal Brahmbhatt, Brian Leber, David W. Andrews,