| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802765 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 5 Pages |
Abstract
⺠Proteins are released from mitochondria during apoptosis. ⺠Several of these proteins can bind to IAPs, but they do not appear to be important regulators of cell death. ⺠During apoptosis, cytochrome c released from mitochondria is essential for activation of Apaf-1, which in turn activates caspases. ⺠AIF and endoG are released from mitochondria during apoptosis, but this is neither sufficient nor required for cell death.
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Authors
David L. Vaux,