Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802784 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 9 Pages |
Abstract
⺠iNOS promoter was the direct transcriptional targets of the C/EBPα, C/EBPβ, and NF-κB. ⺠There was the interaction between NF-κB and C/EBPα/C/EBPβ. ⺠The expression of iNOS was modulated by C/EBPα/C/EBPβ transcription factors. ⺠iNOS involve GCDC induced apoptosis in hepatocytes. ⺠C/EBPα/C/EBPβ could regulate the GCDC-induced apoptosis through iNOS signaling cascade.
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Authors
Kewei Wang, John J. Brems, Richard L. Gamelli, Ai-Xuan Holterman,