| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802786 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 10 Pages |
Abstract
⺠Activity of ASK1-p38 MAPK cascade is upregulated in cardiac muscle differentiation. ⺠TNFα is spontaneously released from differentiating myoblast. ⺠Exogenous TNFα enhances cardiac myogenic differentiation in physiological level. ⺠TNFα-induced H2O2 disrupts ASK1/Trx complex to process myogenic differentiation. ⺠ASK1 promotes p38 MAPK-mediated myogenic differentiation in H2O2-dependent.
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Authors
Tae Gyu Choi, Jisun Lee, Joohun Ha, Sung Soo Kim,