| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802799 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 9 Pages |
Abstract
⺠We review the dilemma of GPCRs with a predominant intracellular localization. ⺠The major focus is on α2C-Adrenoceptors. ⺠GPCRs can be preferentially retained during biosynthesis in the ER and Golgi. ⺠Retention can reflect incomplete processing or targeted protein interactions. ⺠Appropriate stimuli can mobilize GPCRs to the surface or activate them in situ.
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Authors
Maqsood A. Chotani, Nicholas A. Flavahan,