Long and short distance movements of β2-adrenoceptor in cell membrane assessed by photoconvertible fluorescent protein dendra2-β2-adrenoceptor fusion

► Mobility of β2-adrenoceptors follows a hindered diffusion in the cell membrane. ► This process is apparently independent of the receptor activity. ► Large scale movements of the receptor is explainable by its mesoscopic diffusion. ► Mathematical and experimental techniques are provided to investigate such processes. ► Results are discussed in terms of regulation of receptor functions.