Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802804 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 7 Pages |
Abstract
⺠KLK7 and MMP-9 are expressed in pancreatic, breast, cervical, and ovarian cancers. ⺠KLK7 cleaves proMMP-9 to produce a unique truncated, active gelatinase. ⺠Active MMP-9 lacking the hemopexin domains may have altered substrate specificities.
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Authors
Vishnu C. Ramani, Gur P. Kaushal, Randy S. Haun,