| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802840 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 11 Pages |
Abstract
⺠Expression of DMPK in the cytosol induces formation of stellar actomyosin stress fibers. ⺠Stellar stress fiber formation is accompanied by augmented phosphorylation of MLC2. ⺠Myoblasts expressing active cytosolic DMPK display altered cell morphology and motility. ⺠Early steps in myogenesis are delayed upon DMPK activity expression in the cytosol. ⺠High cytosolic DMPK activity during myogenesis supports formation of myosacs.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Susan A.M. Mulders, Remco van Horssen, Lieke Gerrits, Miranda B. Bennink, Helma Pluk, Roelie T. de Boer-van Huizen, Huib J.E. Croes, Mietske Wijers, Fons A.J. van de Loo, Jack Fransen, Bé Wieringa, Derick G. Wansink,