| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802843 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 7 Pages |
Abstract
⺠Gastrins bind two ferric ions with micromolar affinity. ⺠Binding of iron to non-amidated gastrins is essential for biological activity. ⺠Gastrin interacts with, and may catalyse the loading of, transferrin with iron. ⺠Concentrations of circulating gastrins are increased in hemochromatosis. ⺠Transferrin saturation positively correlates with circulating gastrins.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Suzana Kovac, Gregory J. Anderson, Graham S. Baldwin,