Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802858 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 5 Pages |
Abstract
⺠Calcium signaling plays a significant role in the process of osteoclastogenesis. ⺠The RANKL receptor utilizes calcium signaling and activation of NFAT to drive differentiation of osteoclasts. ⺠Recent studies demonstrate that a key component of osteoclast calcium signaling involves influx through plasma membrane channels, including members of the TRP channel superfamily, as well as store-operated channels.
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Authors
Sung-Yong Hwang, James W. Jr.,