| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802862 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 11 Pages |
Abstract
⺠The Ca2+ in the mitochondria is crucial for cell fate. ⺠The localization of the IP3 receptors determines the Ca2+ uptake in the mitochondria. ⺠IP3 receptor function and localization is regulated by protein-protein interactions. ⺠IP3 receptors interact with mitochondrial Ca2+ uptake sites. ⺠The strength of the interactions affect the occurrence of apoptosis or autophagy.
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Authors
Jean-Paul Decuypere, Giovanni Monaco, Geert Bultynck, Ludwig Missiaen, Humbert De Smedt, Jan B. Parys,