| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802864 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 11 Pages |
Abstract
⺠In vivo microglia rarely show Ca2+ transients at rest but reliably respond with rapid Ca2+ signals to damage of an individual neuron in their vicinity. ⺠Damage-induced Ca2+ transients (DICTs) have large amplitudes and are strictly localized to microglia dwelling within a 50-μm vicinity of a damaged neuron. ⺠DICTs require Ca2+ release from intracellular stores likely caused by an activation of metabotropic P2Y receptors.
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Authors
Gerhard Eichhoff, Bianca Brawek, Olga Garaschuk,