Article ID Journal Published Year Pages File Type
10802877 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2011 13 Pages PDF
Abstract
► Differentiating myoblasts downregulate S100B expression via p38 MAPK. ► Serum mitogens upregulate S100B expression in myoblasts. ► Myoblasts induced to quiescence downregulate S100B expression. ► Downregulation of S100B is required for efficient myoblast differentiation. ► Downregulation of S100B is required for myoblast to attain quiescence in vitro.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
S100B in myoblasts regulates the transition from activation to quiescence and from quiescence to activation and reduces apoptosis
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