| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802884 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 8 Pages |
Abstract
⺠Histone chaperone FACT has at least two distinct chromatin-binding modes during DNA replication. ⺠An initial rapid binding of FACT independent of DNA replication events and a latter binding initiating after origin licensing essential for DNA replication. ⺠Cdc6 can inhibit the latter binding of FACT. ⺠This biphasic behavior of FACT may thus be a critical basis in elucidating the cross-talk between DNA replication and chromatin-modifying factors.
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Authors
Lena R. Kundu, Masayuki Seki, Nanae Watanabe, Hiromu Murofushi, Asako Furukohri, Shou Waga, Alan J. Score, J. Julian Blow, Masami Horikoshi, Takemi Enomoto, Shusuke Tada,