Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802901 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 9 Pages |
Abstract
⺠TRIM29 binds to Tip60, which functions as a cellular acetyltransferase. ⺠Overexpression of TRIM29 promotes degradation and changes localization of Tip60. ⺠TRIM29 reduces acetylation of p53 at lysine 120 by Tip60. ⺠TRIM29 suppresses apoptosis induced by UV irradiation in HCT116 cell lines.
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Authors
Takuya Sho, Tadasuke Tsukiyama, Tomonobu Sato, Takeshi Kondo, Jun Cheng, Takashi Saku, Masahiro Asaka, Shigetsugu Hatakeyama,