Article ID Journal Published Year Pages File Type
10802901 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2011 9 Pages PDF
Abstract
► TRIM29 binds to Tip60, which functions as a cellular acetyltransferase. ► Overexpression of TRIM29 promotes degradation and changes localization of Tip60. ► TRIM29 reduces acetylation of p53 at lysine 120 by Tip60. ► TRIM29 suppresses apoptosis induced by UV irradiation in HCT116 cell lines.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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