| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803717 | Biochimie | 2013 | 8 Pages |
Abstract
⺠Translationally controlled tumor protein (TCTP), also known as HRF, shows cytokine-like activity. ⺠TCTP exhibits cytokine-like functions only after it is modified by proteases, oxidants, or IgE in the inflamed sites. ⺠This review shows that dimerization is the critical modification of TCTP responsible for its cytokine-like activity. ⺠It further discusses the clinical relevance of dimerized TCTP to allergic diseases, and in the therapy of these diseases.
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Authors
Miyoung Kim, Jeehye Maeng, Kyunglim Lee,