| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803718 | Biochimie | 2013 | 13 Pages |
Abstract
⺠The review is devoted to novel bioactive lysophospholipids: LPI, LPE, LPS, LPG, LPC. ⺠We summarize their in vivo distribution and biosynthesis pathways. ⺠Those LPLs regulate fundamental cellular functions by modulating multiple targets. ⺠They alter the structure and fluidity of lipid rafts. ⺠We comprehend the progress in deorphanizing GPCRs for LPC, LPS, LPI, LPG and LPE.
Keywords
LPLIAPS1PPLCLPAlysophosphatidylethanolamineLPELPColeoylethanolamideLPIFPRL1formyl peptide receptor like-1SPCTrpLPGLPTCMCLPSG-protein coupled receptorsHODEOEAROSALPIntestinal alkaline phosphataseAlkaline phosphataseSphingosylphosphorylcholineSphingosine-1-phosphatelysophosphatidic acidhydroxyoctadecadienoic acidcritical micelle concentrationphosphatidylcholinephosphatidylethanolaminePhosphatidylserinephospholipase CPhospholipasesPhospholipidLysophosphatidylcholinelysophosphatidylglycerolLysophosphatidylserinelysophospholipidLysophospholipidsLysophosphatidylinositoltransient receptor potentialReactive oxygen species
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Authors
Anna Grzelczyk, Edyta Gendaszewska-Darmach,