| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803742 | Biochimie | 2013 | 9 Pages |
Abstract
⺠Chalcone A1 reduced the cell viability of six leukemia cell lines. ⺠A1 is non-cytotoxic to peripheral blood lymphocytes and normal human fibroblasts. ⺠A1 caused cell cycle arrest in all phases according to the cell line. ⺠Cells treated with A1 demonstrated morphological characteristics of apoptosis. ⺠Apoptosis was confirmed by Annexin V-FITC method and by DNA fragmentation.
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Authors
Mariana Franzoni Maioral, Pâmela Cristina Gaspar, Gabriela Regina Rosa Souza, Alessandra Mascarello, Louise Domeneghini Chiaradia, Marley Aparecida LicÃnio, Ana Carolina Rabello Moraes, Rosendo Augusto Yunes, Ricardo José Nunes,