Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10803744 | Biochimie | 2013 | 6 Pages |
Abstract
⺠Some IQ-motif peptides derived from IQGAP2 and IQGAP3 have antimicrobial activity. ⺠In general, these peptides have low haemolytic activity. ⺠Those peptides with antimicrobial activity tend to bind to LPS. ⺠Some of the peptides permeabilise the bacterial membrane. ⺠IQ-motifs may provide a rich source for the design of novel antimicrobial peptides.
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Authors
Denise T.F. McLean, Fionnuala T. Lundy, David J. Timson,