Article ID Journal Published Year Pages File Type
10803746 Biochimie 2013 8 Pages PDF
Abstract
▶ Suppressor tRNA proved species-specific toxic to host cells. ▶ Species-specific toxicity of suppressor tRNA is dependent on its orthogonality. ▶ The species-specific toxicity could be used to screen orthogonal suppressor tRNA. ▶ A convenient screening system for orthogonal suppressor tRNA was developed. ▶ It could serve as a general platform for generating tRNA/aaRS pairs.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Screening system for orthogonal suppressor tRNAs based on the species-specific toxicity of suppressor tRNAs
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