Article ID Journal Published Year Pages File Type
10803749 Biochimie 2012 6 Pages PDF
Abstract
► Thermal denaturation of hexokinase A MG state at pH 2.5 is non-cooperative. ► Ethylene glycol populates non-native and non-cooperative ensemble at pH 2.5. ► Stabilizing polyol osmolytes populate native-like cooperative intermediate state at pH 2.5. ► The cooperative intermediate state binds to the substrate glucose.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , ,