Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10803749 | Biochimie | 2012 | 6 Pages |
Abstract
⺠Thermal denaturation of hexokinase A MG state at pH 2.5 is non-cooperative. ⺠Ethylene glycol populates non-native and non-cooperative ensemble at pH 2.5. ⺠Stabilizing polyol osmolytes populate native-like cooperative intermediate state at pH 2.5. ⺠The cooperative intermediate state binds to the substrate glucose.
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Authors
Prasanna K. Devaraneni, Neeraj Mishra, Rajiv Bhat,