Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10803750 | Biochimie | 2013 | 9 Pages |
Abstract
⺠BEL was the most powerful inhibitor of iPLA2 among the different molecules tested. ⺠The retina was more susceptible than the brain to iPLA2 inhibition by BEL. ⺠Intraperitoneal injection of BEL in mice inhibited retinal iPLA2 activity by 50%. ⺠Repeated treatments with BEL in mice maintained such an inhibition over seven days.
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Authors
Sarah Saab-Aoudé, Alain M. Bron, Catherine P. Creuzot-Garcher, Lionel Bretillon, Niyazi Acar,