Article ID Journal Published Year Pages File Type
10803760 Biochimie 2013 5 Pages PDF
Abstract
► We investigated ABCA1 molecular function by tagging and isolating the protein. ► The 1D4 tag did not modify the protein expression/localization within the cells. ► The 1D4 tag did not impair ABCA1-dependent cholesterol efflux to apo A-I. ► Solid-phase binding assays showed no direct binding of cholesterol to ABCA1. ► Solid-phase binding assays showed no direct binding of apo A-I to ABCA1 either.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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