| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803791 | Biochimie | 2012 | 12 Pages |
Abstract
⺠In type 2 diabetes tricarboxylic acid cycle electron donor are overproduced. ⺠Mitochondrial proton gradient increases. ⺠Mitochondrial electron transporter lifetime increases. ⺠Leaked electrons combine with respiratory oxygen resulting in superoxide anion production. ⺠A vicious circle of pathway derived ROS installs activating pathologic pathways.
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Authors
Asma Kassab, Agnieszka Piwowar,