Article ID Journal Published Year Pages File Type
10803844 Biochimie 2012 10 Pages PDF
Abstract
► Staphylococcus aureus secretes homologous cysteine proteinases staphopains A, B and C. ► Their divergent roles in pathogenesis of S. aureus may be linked to their substrate specificity. ► We use a combination of diverse approaches to profile these related proteases. ► In summary, only P2 residue distinguish the substrate specificity of the staphopains. ► Substrate preferences of staphopains B and C differ from those of staphopain A.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , , , , , , , , , , , ,