| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803862 | Biochimie | 2012 | 7 Pages |
Abstract
⺠We show that Cathepsin S is upregulated in colorectal tumour cells by chemotherapy. ⺠Inhibition of Cathepsin S with Fsn0503 enhances the efficacy of chemotherapy. ⺠Cathepsin S inhibitors may have clinical utility in chemotherapy regimes.
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Authors
Roberta E. Burden, Julie A. Gormley, Diana Kuehn, Claire Ward, Hang Fai Kwok, Mihaela Gazdoiu, Angela McClurg, Thomas J. Jaquin, James A. Johnston, Christopher J. Scott, Shane A. Olwill,