Article ID Journal Published Year Pages File Type
10803863 Biochimie 2012 9 Pages PDF
Abstract
► DNA compaction induced by BBR3464, at ri 0.03, is more severe than that induced by cisplatin, at ri 1.5. ► BBR3464 and cisplatin both can form DNA loop structures as a result of long-range DNA cross-links. ► The trinuclear BBR3464 forms macroloops and microloops both, while the mononuclear cisplatin forms primarily microloops.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , ,