| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803876 | Biochimie | 2013 | 10 Pages |
Abstract
⺠Membrane-bound mucins share conserved modular domains such as EGF and SEA. ⺠Transmembrane mucins are characterised by an O-glycosylated extracellular subunit. ⺠The EGF-like domains mediate the interactions with different signalling pathways. ⺠We predict the EGF-like and SEA mucin 3D structures using the Phyre 2 server. ⺠Spliced mucins lacking functional domains may show altered biological functions.
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Authors
Nicolas Jonckheere, Nicolas Skrypek, Frédéric Frénois, Isabelle Van Seuningen,