| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803880 | Biochimie | 2013 | 7 Pages |
Abstract
⺠Mpl catalyses the addition of tripeptide l-Ala-γ-d-Glu-meso-diaminopimelate to UDP-MurNAc during peptidoglycan recycling. ⺠Ten tripeptides l-Ala-γ-d-Glu-Xaa were synthesised. ⺠Tripeptide with Xaa = ε-d-Lys is an excellent alternate substrate of Escherichia coli Mpl in vitro.
Keywords
APM2,6-diaminopimelic acidMurNAcmatrix-assisted laser desorption/ionisation time-of-flightN-methylmorpholinet-butyloxycarbonylNMMN-hydroxysuccinimideHOSUBOCHEPHOBtMPLDCCAcOHTFAMALDI-TOFEDCTLCIPTGDCMDMF1-ethyl-3-(3-dimethylaminopropyl)carbodiimideN,N′-dicyclohexylcarbodiimideAbu2-aminobutyric acidTrifluoroacetic acidAcetic acidEscherichia coliisopropyl β-D-thiogalactopyranosideBenzylbenzyloxycarbonyldimethylformamideDichloromethaneMethylNlenorleucineNvanorvalinehydroxybenzotriazoleHPLChigh-performance liquid chromatographythin-layer chromatography
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Authors
Mireille Hervé, Andreja KovaÄ, Cécile Cardoso, Delphine Patin, Boris Brus, Hélène Barreteau, Dominique Mengin-Lecreulx, Stanislav Gobec, Didier Blanot,