Article ID Journal Published Year Pages File Type
10803886 Biochimie 2013 8 Pages PDF
Abstract
► HGF regulates NADPH oxidase by a biphasic mechanism. ► The first mechanism (early response) increases NADPH oxidase-derived ROS. ► ROS are required for Nrf2 activation. ► The second one (late response) downregulates NADPH oxidase components. ► Both mechanisms are related to cell survival.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Biphasic regulation of the NADPH oxidase by HGF/c-Met signaling pathway in primary mouse hepatocytes
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