Article ID Journal Published Year Pages File Type
10803887 Biochimie 2013 11 Pages PDF
Abstract
► Binding affinities of polyamines with G-quadruplex DNA were determined by Q-TOF-MS. ► Polyamines can induce conformational changes of the five selected G-quadruplex DNA. ► The structural stability of humtel24 can be improved after combining with polyamines. ► Morphological changes of humtel24 after combining with polyamines were observed by AFM. ► Binding mechanisms of G-quadruplex DNA and polyamines were discussed.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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