Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10803891 | Biochimie | 2013 | 10 Pages |
Abstract
⺠Misfolded multi-transmembrane (MTM) proteins trigger clearance of yeast prions. ⺠Excess MTM protein induces HSR, but not UPR, and abnormally accumulates in the ER. ⺠The get3Πdeletion mutant disables the prion clearance. ⺠The GET pathway might be involved in quality control of MTM proteins and prions.
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Authors
Chie Arai, Hiroshi Kurahashi, Masao Ishiwata, Keita Oishi, Yoshikazu Nakamura,